Aspirin Allergy and Desensitization

The symptoms of aspirin respiratory reactions are not limited to eye-watering, sneezing, skin rash, and
wheezing. Patients with nasal polyps, asthma, and chronic sinusitis often display intolerance to aspirin.
The condition can be corrected by aspirin desensitization which involves gradually increasing the dose of
aspirin to treat sensitivity, such as aspirin-exacerbated respiratory disease (AERD).

In addition, individuals with AERD experience respiratory symptoms from aspirin and non-steroidal anti-
inflammatory drugs (NSAIDs) like naproxen and ibuprofen. Aspirin desensitization allows an individual to
take aspirin even if they have experienced severe respiratory reactions.

Symptoms

After desensitization, individuals can experience various signs that may warrant them to call a doctor. Some of these symptoms would include the following:

• Swelling of tongue or lips
• Nausea
• Challenge with swallowing anything
• Hives
• Belly pain

Diagnosis

An aspirin allergy test can be done by placing a small granule of aspirin on a patient’s tongue. Allergy
symptoms appear within a few minutes in case of a positive reaction. If a positive response occurs, further
absorption is stopped by removing the aspirin granules and cleaning the mouth with dilute acetic acid.

In addition, small doses of adrenalin can control the symptoms further. It’s advisable to carry the test on
every allergic individual before administering aspirin. The test can be avoided if it’s certain that the person
tolerates aspirin. Further, small doses of adrenalin can control the symptoms.

Management and Treatment

Aspirin desensitization induces tolerance to aspirin, and people with AERD can use it. The provider starts by giving an individual dose of aspirin and monitors the results. The treatment continues until the dose reaches a point where it causes no symptoms.

The dose gets higher and higher to the point that the body starts accommodating the drug without reacting. The process is done in a few days and the person has to continue on full dosage of aspirin to remain desensitized after the completion of the process.

How Can We Help?

If you experience any of the above symptoms or other related signs, seek medical help from a qualified practitioner. The doctor may ask you a few questions and advise you accordingly. This can help prevent further complications that can be severe and life-threatening. If you have questions about our services or want to schedule an appointment, contact us today.